Hall adds that, in her experience, around 75 percent of patients who take prednisone (a common prescription steroid) for an extended period of time gain weight. While the effects of weight gain are short-lived, other common side effects include mood problems, headaches, anorexia, and sleep problems. In some cases, the prednisone may not be able to adequately reduce weight loss.
She is calling for further research to see if a more powerful form of prednisone—something that doesn’t require daily administration—could help obese patients overcome their weight problems. According to the Center for Disease Control and Prevention, obesity among children and young adults is a major public health challenge.
“A combination of physical therapy and diet change may be one possible option,” adds Meech, noting that her initial research will be on how to apply the model to obese people.
The research was published online Nov. 12 in The journal Obesity.
One in five of them filled a short-term prescription for oral corticosteroids such as prednisone sometime in the three-year study period, while 1,300 were on continuous long-term use by the end of the study and had been prescribed short-term glucocorticosteroids.
In other studies, researchers compared the use of short-term corticosteroids with continuous use. Results showed the latter was significantly more effective at relieving symptoms.
“This study shows that short-term use of glucocorticosteroids is an effective tool for treating osteoarthritis pain, and that long-term usage of short-term corticosteroids appears to be a very effective tool in relieving some pain,” said Dr. Stephen Fournier, the study’s lead author, a orthopedic surgeon and clinical faculty member at the VA Palo Alto Health Care System.
The study was published online June 26 at PLOS ONE.
This study was supported by grants A161052, A170953, A170767, and A161253 from the National Institutes of Health.
Prednisone is a steroid prescription drug that may come as a liquid solution, an immediate or delayed-release tablet all of which can be taken orally, by injection, as a liquid, or by both methods. Many doctors use the steroid to treat a condition that has an exaggerated inflammatory response but that typically has little or no effect on an individual’s ability to exercise, such as asthma. Patients should contact their physician or healthcare provider as soon as they feel a sudden change in symptoms, such as a headache, fever, muscle pain, weight loss, etc, prednisone for dogs without a vet prescription. or if they are having difficulties with their activity level or health care professionals should be consulted to determine if there are potential medical causes of this condition.
Patients on any form of steroid should be monitored closely and should also be told of all other treatments that can be prescribed, such as:
Anti-inflammatories – Injection therapy may help some people get through a bout of symptoms, but may not work for everyone. In addition, a prescription drug medication (such as ibuprofen, naproxen, or celecoxib) should always be prescribed if patients are experiencing a prolonged flare-up or serious problem such as a persistent weight gain.
– Injection therapy may help some people get through a bout of symptoms, but may not work for everyone. In addition, a prescription drug medication (such as ibuprofen, naproxen, or celecoxib) should always be prescribed if patients are experiencing a prolonged flare-up or serious problem such as a persistent weight gain. Cardiovascular disease – Certain medications may help decrease risk for serious health problems such as heart attack, stroke, or heart-related heart failure. If you’re feeling especially dizzy or have heart-related symptoms before a steroid use, you should contact your physician to discuss your options.
– Certain medications may help decrease risk for serious health problems such as heart attack, stroke, or heart-related heart failure. If you’re feeling especially dizzy or have heart-related symptoms before a steroid use, you should contact your physician to discuss your options. Diabetes – Diabetic patients should take a diabetes medication with them. This medication works to help regulate the body’s production of insulin and other hormones that help regulate blood sugar levels and metabolism.
– Diabetic patients should take a diabetes medication with them. This medication works to help regulate the body’s production of insulin and other hormones that help regulate blood sugar levels and metabolism. High blood pressure – There’s no risk to have a high blood pressure when taking a prescription steroid. This medication helps the body to produce energy that has the effect of reducing the risk
Prednisone is a steroid prescription drug that may come as a liquid solution, an immediate or delayed-release tablet all of which can be taken orallyin doses up to 100 mg twice a day.
Niacinamide, a vitamin B-3 drug that increases the body’s production of vitamin B-3, also is anabolic steroid therapy because it works differently than other steroids or the more common and effective aldosterone analogs. Niacinamide (d-Glucopyran) works to reduce stress and anxiety by increasing the synthesis of the neurotransmitters serotonin and norepinephrine, which in turn affect the stress-coping system.
The Bottom Line
The drug is a potent aldosterone analog and is a very effective steroid. Niacinamide inhibits stress and anxiety, helping to prevent and treat a variety of medical problems, including osteoporosis, muscle wasting, and chronic fatigue.
Hall adds that, in her experience, around 75 percent of patients who take prednisone (a common prescription steroid) for an extended period of time gain weightwithout it. She also believes that the drugs are the primary reason that obese patients have trouble losing weight for many years. “It’s a false hope,” she says. In the study, the researchers compared four groups of healthy adult men and women that were randomized to prednisone or placebo for 20 weeks, prednisone for dogs without a vet prescription. The active drug group ate roughly the same amount of food – 2,000 calories a day, on average – as the placebo group.
The active group, on average, had a weight gain of about 9 pounds. The active drug group averaged 13.25 pounds of body weight gain, a weight gain of approximately five pounds per week.
This weight gain was accompanied by a steady rise in fasting blood glucose levels and weight loss. Over the course of the study, the average weight increased by three pounds, about two pounds per week for each individual, and weight loss decreased by one pound per week over the course of the study.
“What we’re seeing is that there’s no difference in metabolic profile between the groups,” says Blanchard, a professor of medicine at NYU Langone Medical Center who was not involved with the research. “In a population that is already obese,” he adds, “the weight gain makes it worse. It just makes it worse.”
The researchers suggest that future research in obese people with prednisone use could be more aggressive.
Prednisone for dogs without a vet prescription
The data may be particularly useful for the U.S. military personnel who are prescribed prednisone for treatment of joint pain, prednisone vet without for a dogs prescription. The study shows that the drug may decrease the risk of muscle deterioration and muscle wasting in soldiers, even when other treatments – including weight loss, nutritional therapy, and other forms of therapy – have failed. Blanchard says this data could be particularly valuable as the Pentagon looks to reduce the number of troops serving in combat zones.
He cautions that the data has limitations. The participants were recruited in New York, not in Japan, and while it is possible that the participants in both groups responded poorly to the treatment, Blanchard believes the large, long-term effects of the treatment have been observed.
The study was funded by the National Institutes of Health, which provided an M.B.A. to Blanchard and an American Indian Tribe grant to Nisbet.
This research is the latest in a growing number of papers that have documented how the drugs and other therapies used to manage joint pain can increase the risk of obesity. For example, in a study published